Personality traits such as novelty seeking (NS) are associated with substance dependence but the mechanism underlying this association remains uncertain. Previous studies have focused on the role of the dopamine pathway. Examine the relationships between allelic variants of the catechol-O-methyltransferase (COMT) gene. NS personality traits. https://www.markbroyard.com/mega-pick-michigan-state-spartans-secchia-stadium-on-sale-super-sale/